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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKD1
All Species:
35.76
Human Site:
S448
Identified Species:
78.67
UniProt:
Q15139
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15139
NP_002733.2
912
101704
S448
R
H
Y
W
R
L
D
S
K
C
I
T
L
F
Q
Chimpanzee
Pan troglodytes
XP_001170806
912
101668
S448
R
H
Y
W
R
L
D
S
K
C
I
T
L
F
Q
Rhesus Macaque
Macaca mulatta
XP_001114639
912
101836
S448
R
H
Y
W
R
L
D
S
K
C
I
T
L
F
Q
Dog
Lupus familis
XP_851386
884
99023
S420
R
H
Y
W
R
L
D
S
K
C
I
T
L
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q62101
918
102049
S454
R
H
Y
W
R
L
D
S
K
C
I
T
L
F
Q
Rat
Rattus norvegicus
Q9WTQ1
918
102025
S454
R
H
Y
W
R
L
D
S
K
S
I
T
L
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512992
948
106688
S484
R
H
Y
W
R
L
D
S
K
C
I
T
L
F
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685219
878
98838
S412
R
H
Y
W
R
L
D
S
K
C
I
T
L
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61267
476
54243
A71
L
N
N
D
E
F
T
A
G
R
G
E
A
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45818
1070
120565
T650
K
H
Y
W
R
L
D
T
K
G
I
T
M
Y
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39009
513
58614
N108
S
R
N
G
T
F
I
N
G
N
R
L
V
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
92
N.A.
92.5
93.1
N.A.
81.3
N.A.
N.A.
80.1
N.A.
20.1
N.A.
43.7
N.A.
Protein Similarity:
100
99.5
99.3
93.9
N.A.
95
95.4
N.A.
86.3
N.A.
N.A.
86.7
N.A.
32
N.A.
56.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
N.A.
N.A.
100
N.A.
0
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
N.A.
N.A.
100
N.A.
13.3
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
82
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
19
0
0
0
0
0
0
0
73
0
% F
% Gly:
0
0
0
10
0
0
0
0
19
10
10
0
0
0
0
% G
% His:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
82
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
82
0
0
0
0
10
10
% K
% Leu:
10
0
0
0
0
82
0
0
0
0
0
10
73
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
19
0
0
0
0
10
0
10
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% Q
% Arg:
73
10
0
0
82
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
73
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
10
10
0
0
0
82
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
82
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _